MMP3 Antikörper (AA 317-327)

Produktnummer ABIN6937879

Dieses Anti-MMP3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MMP3 in ELISA und Coat. Geeignet für Human.

Kurzübersicht für MMP3 Antikörper (AA 317-327) (ABIN6937879)

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MMP3 Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Klon: 1B4

Produktdetails anti-MMP3 Antikörper

Bindungsspezifität: AA 317-327

Spezifität: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment corresponding to amino acids 317-327 of human MMP3.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (Use at 2-4 μg/mL for coating) (Order without BSA)Optimal dilution for a specific application should be determined.

Positive_Control: A431 cells. Prostate or Lung Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu MMP3

Target: MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))

Andere Bezeichnung: MMP3

Hintergrund: CHDS6, Matrix metalloproteinase 3, Matrix metalloproteinase-3, MMP3, Proteoglycanase, SL1, STMY1, STR1, Stromelysin-1, Transin 1,MMP3 (Marker of Metastasis and Rheumatoid Arthritis)
Cellular localisation: Cytoplasmic and Extracellular Matrix

Molekulargewicht: 57kDa

Gen-ID: 4314, 375129

UniProt: P08254