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Rekombinanter Cytokeratin 18 Antikörper

Der Kaninchen Monoklonal Anti-Cytokeratin 18-Antikörper wurde für WB, IF, FACS und IHC (f) validiert. Er ist geeignet, Cytokeratin 18 in Proben von Human zu detektieren.
Produktnummer ABIN6937689

Kurzübersicht für Rekombinanter Cytokeratin 18 Antikörper (ABIN6937689)

Target

Alle Cytokeratin 18 (KRT18) Antikörper anzeigen
Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 331
  • 155
  • 130
  • 76
  • 67
  • 58
  • 53
  • 50
  • 42
  • 39
  • 35
  • 35
  • 35
  • 18
  • 8
  • 8
  • 7
  • 6
  • 4
  • 3
  • 2
  • 1
Human

Wirt

  • 191
  • 182
  • 3
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 230
  • 146
  • 3
Monoklonal

Konjugat

  • 194
  • 30
  • 23
  • 13
  • 10
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation

  • 314
  • 193
  • 122
  • 121
  • 73
  • 69
  • 59
  • 58
  • 54
  • 45
  • 40
  • 32
  • 18
  • 8
  • 8
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon

KRT18-2819R
  • Spezifität

    This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

    Keine Kreuzreaktivität

    Huhn, Xenopus laevis

    Kreuzreaktivität (Details)

    Human. Mouse. Rat. Hamster. Ferret. Cow. Pig. Cat. Dog. Sheep. Goat. Horse. Marmoset monkey. Does not react with Chicken or Xenopus.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant human full-length KRT18 protein

    Isotyp

    IgG
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells),Western Blot (1-2 μg/mL),Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HCT116, MCF-7, HeLa cells, Breast Cancer.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

    Andere Bezeichnung

    KRT18

    Hintergrund

    Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18,Cytokeratin 18 (KRT18)
    Cellular localisation: Cytoplasmic

    Molekulargewicht

    45kDa

    Gen-ID

    3875, 406013

    UniProt

    P05783

    Pathways

    Apoptose, Caspase Kaskade in der Apoptose
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