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HLA-ABC Antikörper

HLA-ABC Reaktivität: Human FACS, IF Wirt: Maus Monoclonal 246-B8-E7 unconjugated
Produktnummer ABIN6937393
  • Target Alle HLA-ABC Antikörper anzeigen
    HLA-ABC
    Reaktivität
    • 68
    • 23
    • 16
    • 14
    • 13
    • 12
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 9
    • 3
    Maus
    Klonalität
    • 59
    • 9
    Monoklonal
    Konjugat
    • 31
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HLA-ABC Antikörper ist unkonjugiert
    Applikation
    • 53
    • 17
    • 17
    • 10
    • 10
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Spezifität
    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
    Kreuzreaktivität (Details)
    Human. Mouse. Non-Human primates.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Human peripheral blood leukocytes
    Klon
    246-B8-E7
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product HLA-ABC Primärantikörper
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: THP-1 and Jurkat cells. Tonsil or lymph node.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    HLA-ABC
    Andere Bezeichnung
    HLA-A, HLA-B, HLA-C (HLA-ABC Produkte)
    Synonyme
    HLAA antikoerper, major histocompatibility complex, class I, A antikoerper, HLA-A antikoerper
    Hintergrund
    HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC,HLA-ABC (MHC I)
    Cellular localisation: Cell surface
    Molekulargewicht
    ~41kDa
    Gen-ID
    3105, 3106, 3107
    UniProt
    P01889, P30443, P30499
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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