CD55 Antikörper
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- Target Alle CD55 Antikörper anzeigen
- CD55 (Complement Decay-Accelerating Factor (CD55))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD55 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), DNA Microscopy (DNA Mic), DNA Microscopy (DNA Mic)
- Spezifität
- Recognizes a single chain glycoprotein of 70 kDa, identified as CD55. This MAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. Anti-CD55 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Human umbilical vein endothelial cells (HUVEC)
- Klon
- F4-29D9
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD55 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat, HUT-78, K562, YT, U937, MG63 and human lymphocytes. Human lymph nodes and tonsils.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- CD55 (Complement Decay-Accelerating Factor (CD55))
- Andere Bezeichnung
- CD55 (CD55 Produkte)
- Synonyme
- CR antikoerper, CROM antikoerper, DAF antikoerper, TC antikoerper, Daf antikoerper, Daf-GPI antikoerper, Daf1 antikoerper, GPI-DAF antikoerper, CD55 molecule (Cromer blood group) antikoerper, CD55 molecule, decay accelerating factor for complement antikoerper, CD55 antikoerper, Cd55 antikoerper
- Hintergrund
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CD55, CD55 Cromer blood group system, Complement decay-accelerating factor, CROM, DAF, Decay Accelerating Factor for Complement, Decay accelerating factor GPI-form, Decay accelerating factor soluble-form, GPI-DAF,CD55 / Decay Accelerating Factor (DAF)
Cellular localisation: Cell Surface - Molekulargewicht
- 70kDa
- Gen-ID
- 1604, 126517
- UniProt
- P08174
- Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity
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