AMPD3 Antikörper

Produktnummer ABIN6936408

Der Maus Monoklonal Anti-AMPD3-Antikörper wurde für IHC (f) validiert. Er ist geeignet, AMPD3 in Proben von Human zu detektieren.

Kurzübersicht für AMPD3 Antikörper (ABIN6936408)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AMPD3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: AMPD3-901

Produktdetails anti-AMPD3 Antikörper

Spezifität: It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human AMDP3 protein

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: RBC. Fetal liver, Spleen or Placenta.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Andere Bezeichnung: AMPD3

Hintergrund: Adenosine monophosphate deaminase (isoform E), AMP aminohydrolase, AMP deaminase 3, AMP deaminase isoform E, Ampd3, Erythrocyte AMP deaminase, Erythrocyte specific AMP deaminase, Erythrocyte specific protein, Erythrocyte type AMP deaminase, Myoadenylate deaminase,AMP Deaminase, Isoform E (AMPD3) (Erythroid Marker)
Cellular localisation: Cell Surface

Molekulargewicht: ~90kDa

Gen-ID: 272, 501890

UniProt: Q01432