APEX1 Antikörper (Cy3)

Produktnummer ABIN686095

Produktdetails anti-APEX1 Antikörper (Cy3)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEX1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB)

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APEX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Andere Bezeichnung: Ref1/Apex1 (APEX1 Produkte)

Synonyme: apex1 antikoerper, MGC76280 antikoerper, MGC79645 antikoerper, MGC78928 antikoerper, APE antikoerper, APE1 antikoerper, APEN antikoerper, APEX antikoerper, APX antikoerper, HAP1 antikoerper, REF1 antikoerper, Apex antikoerper, REF-1 antikoerper, BAP1 antikoerper, apex1a antikoerper, hm:zehn1532 antikoerper, wu:fc13d11 antikoerper, zgc:66204 antikoerper, Ref-1 antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 antikoerper, APEX nuclease (multifunctional DNA repair enzyme) 1 L homeolog antikoerper, DNA-(apurinic or apyrimidinic site) lyase antikoerper, apurinic/apyrimidinic endonuclease 1 antikoerper, APEX1 antikoerper, apex1 antikoerper, apex1.L antikoerper, CNG03640 antikoerper, CNH01280 antikoerper, nth antikoerper, Spirs_4119 antikoerper, Palpr_0103 antikoerper, Apex1 antikoerper

Hintergrund:

Synonyms: mitochondrial, AP endonuclease 1, Ape1, AP endonuclease class I, AP lyase, APE 1, APE, APE-1, APEN, APEX 1, APEX, APEX nuclease multunctional DNA repair enzyme 1, Apex nuclease 1, APEX nuclease, APEX1, APEX1_HUMAN, Apurinic endonuclease, Apurinic-apyrimidinic endonuclease 1, Apurinic/apyrimidinic abasic endonuclease, Apurinic/apyrimidinic endonuclease 1, Apurinic/apyrimidinic exonuclease, APX, BAP1, Deoxyribonuclease apurinic or apyrimidinic, DNA apurinic or apyrimidinic site lyase, DNA-apurinic or apyrimidinic site lyase, DNA-apurinic or apyrimidinic site lyase, mitochondrial, EC 4.2.99.18, HAP 1, HAP1, Human Apurinic endonuclease 1, Apurinic/Apyrimidic eEndonuclease 1, MGC139790, Multunctional DNA repair enzyme, Redox effector factor 1, Redox factor 1, Redox factor-1, REF 1, REF 1 protein, REF-1, REF1, REF1 protein.

Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene, all encode the same protein. [provided by RefSeq].

Gen-ID: 328

Pathways: DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus