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GRB10 Antikörper (pTyr67)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRB10 in ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN684973

Kurzübersicht für GRB10 Antikörper (pTyr67) (ABIN684973)

Target

Alle GRB10 Antikörper anzeigen
GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

Reaktivität

  • 48
  • 9
  • 8
  • 2
  • 1
Human, Maus

Wirt

  • 42
  • 6
  • 1
Kaninchen

Klonalität

  • 45
  • 4
Polyklonal

Konjugat

  • 39
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GRB10 Antikörper ist unkonjugiert

Applikation

  • 35
  • 18
  • 16
  • 15
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr67

    Kreuzreaktivität

    Human, Maus

    Homologie

    Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human GRB10 around the phosphorylation site of Tyr67 [SL(p-Y)SA]

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

    Andere Bezeichnung

    GRB10

    Hintergrund

    Synonyms: GRB IR, grb-10, GRB10 adaptor protein, GRBIR, Growth factor receptor bound protein 10, Insulin receptor binding protein, Insulin receptor binding protein GRB IR, IRBP, MEG1, RSS.

    Background: GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.

    Gen-ID

    2887

    Pathways

    Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
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