GRB10 Antikörper (pTyr67)
Kurzübersicht für GRB10 Antikörper (pTyr67) (ABIN684973)
Target
Alle GRB10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr67
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Kreuzreaktivität
- Human, Maus
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Homologie
- Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic phosphopeptide derived from human GRB10 around the phosphorylation site of Tyr67 [SL(p-Y)SA]
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Isotyp
- IgG
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Applikationshinweise
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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Andere Bezeichnung
- GRB10
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Hintergrund
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Synonyms: GRB IR, grb-10, GRB10 adaptor protein, GRBIR, Growth factor receptor bound protein 10, Insulin receptor binding protein, Insulin receptor binding protein GRB IR, IRBP, MEG1, RSS.
Background: GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.
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Gen-ID
- 2887
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Pathways
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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