Cyclin E1 Antikörper (pThr77) (HRP)
Kurzübersicht für Cyclin E1 Antikörper (pThr77) (HRP) (ABIN684502)
Target
Alle Cyclin E1 (CCNE1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pThr77
-
Kreuzreaktivität
- Human
-
Homologie
- Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic phosphopeptide derived from human Cyclin E around the phosphorylation site of Thr77
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:300-5000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- Cyclin E1 (CCNE1)
-
Andere Bezeichnung
- Cyclin E
-
Hintergrund
-
Synonyms: CCNE 1, CCNE,CCNE1,Cyclin E1 antibody Cyclin Es,Cyclin Et,CyclinE, G1/S specic cyclin E, CCNE1_HUMAN.
Background: Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
-
Molekulargewicht
- 47kDa
-
Gen-ID
- 898
-
Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
Target
-