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beta Catenin Antikörper (pSer45, pThr41) (Biotin)

CATNB Reaktivität: Human, Ratte ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin

Produktnummer ABIN683955

Datenblatt (PDF)

Target Alle beta Catenin (CATNB) Antikörper anzeigen

beta Catenin (CATNB) (Catenin, beta (CATNB))
Bindungsspezifität
42

26

21

21

20

17

17

17

17

16

16

15

9

8

7

7

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer45, pThr41
Reaktivität
331

247

226

29

23

22

18

18

5

5

5

5

1

1

1

1

1

1

1

1
Human, Ratte
Wirt
270

60

4

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
265

72
Polyklonal
Konjugat
124

21

16

15

15

15

15

15

11

10

9

9

9

9

9

8

4

4

4

4

4

4

1

1

1
Dieser beta Catenin Antikörper ist konjugiert mit Biotin
Applikation
208

159

120

118

73

63

62

48

35

30

22

9

7

4

1

1

1

1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

This phophorylation site is homologous to that of Thr41 + Ser45 in Mouse and Rat.

Kreuzreaktivität

Human, Ratte

Homologie

Mouse,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human Beta-Catenin around the phosphorylation site of Thr41/Ser45

Isotyp

IgG

Top Product

Discover our top product CATNB Primärantikörper
anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Xenopus laevis WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 661-781) antibody
CATNB Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio) WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Schwein, Kaninchen, Schaf, Affe, Hamster, Avian, Cat, Esel, Ziege, Meerschweinchen, Pferd WB, IF Wirt: Ziege Polyclonal unconjugated

anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C901 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB Reaktivität: Human, Maus, Hamster WB, FACS, IP, ICC Wirt: Maus Monoclonal EM-22 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Maus Monoclonal 4A3H3 unconjugated

Applikationshinweise

IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C for 12 months.

Haltbarkeit

12 months
Target

beta Catenin (CATNB) (Catenin, beta (CATNB))

Andere Bezeichnung

Beta Catenin + (CATNB Produkte)

Synonyme

Bfc antikoerper, Catnb antikoerper, Mesc antikoerper, CTNNB antikoerper, MRD19 antikoerper, armadillo antikoerper, ctnnb antikoerper, id:ibd2058 antikoerper, wu:fb73e10 antikoerper, wu:fi81c06 antikoerper, wu:fk25h01 antikoerper, beta-catenin antikoerper, ctnnb1 antikoerper, CHBCAT antikoerper, catenin (cadherin associated protein), beta 1 antikoerper, catenin beta 1 antikoerper, catenin (cadherin-associated protein), beta 1 antikoerper, catenin beta 1 L homeolog antikoerper, Ctnnb1 antikoerper, CTNNB1 antikoerper, ctnnb1 antikoerper, ctnnb1.L antikoerper

Hintergrund

Synonyms: CTNNB, MRD19, armadillo, Catenin beta-1, Beta-catenin, CTNNB1, OK/SW-cl.35, PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML.

Gen-ID

1499

UniProt

P35222

Pathways

Peptide Hormone Metabolism