MAP3K11 Antikörper (AA 355-460) (Biotin)
Kurzübersicht für MAP3K11 Antikörper (AA 355-460) (Biotin) (ABIN682575)
Target
Alle MAP3K11 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 355-460
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Spezifität
- Due to the similarity of this protein to MLK1 2 and 4, there is a chance that this antibody will cross-react based on homology.
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Cow,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human MLK3
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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Andere Bezeichnung
- MLK3
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Hintergrund
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Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11
Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
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Molekulargewicht
- 94kDa
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Gen-ID
- 4296
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UniProt
- Q16584
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Pathways
- MAPK Signalweg, Interferon-gamma Pathway
Target
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