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SMO Antikörper (AA 551-650)

Name: SMO Antikörper (AA 551-650)
SKU: ABIN680908
Price: 357.7 EUR
Availability: InStock

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMO in WB, ELISA, IHC (p) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 3+ Publikationen erwähnt.

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Smoothened/SMO Polyclonal Antibody, Unconjugated (ABIN680908) at 1:200, followed by conjugation to the secondary antibody and DAB staining (SMO Antikörper (AA 551-650))

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-Smoothened/SMO Polyclonal Antibody, Unconjugated (ABIN680908) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. (SMO Antikörper (AA 551-650))

L1 rat kidney lysates L2 rat brain lysates probed with Anti Smoothened/SMO Polyclonal Antibody, Unconjugated (ABIN680908) at 1:200 overnight at 4 °C. (SMO Antikörper (AA 551-650))

SDS

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Smoothened/SMO Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (SMO Antikörper (AA 551-650))

IHC (p)

4 Abbildungen

(3 Referenzen)

Produktnummer ABIN680908

Datenblatt (PDF)

Kurzübersicht für SMO Antikörper (AA 551-650) (ABIN680908)

Target

Alle SMO Antikörper anzeigen

SMO (Smoothened Homolog (Drosophila) (SMO))

Reaktivität

Human, Maus, Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser SMO Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Bindungsspezifität
14

8

8

6

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 551-650

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human Smoothened

Isotyp

IgG
anti-Smoothened Homolog (Drosophila) (SMO) (AA 554-787) antibody
SMO Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 28-233) antibody
SMO Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) antibody
SMO Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 3D10 unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (1st Extracellular Domain) antibody
SMO Reaktivität: Human, Maus IHC, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (N-Term) antibody
SMO Reaktivität: Human, Maus, Ratte, Hund, Fledermaus, Rind (Kuh), Hamster, Pferd, Affe, Schwein, Kaninchen WB, IHC, IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 68-117) antibody
SMO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (AA 653-787) antibody
SMO Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1D9 unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (N-Term) antibody
SMO Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (N-Term) antibody
SMO Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

anti-Smoothened Homolog (Drosophila) (SMO) (pSer611), (pSer615), (pSer616) antibody
SMO Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Zhou, Zhou, Liu, Shen: "GDC-0449 improves the antitumor activity of nano-doxorubicin in pancreatic cancer in a fibroblast-enriched microenvironment." in: Scientific reports, Vol. 7, Issue 1, pp. 13379, (2019) (PubMed).

Wang, Zhang, Bai, Wang, Du: "Baicalin Attenuates Alcoholic Liver Injury through Modulation of Hepatic Oxidative Stress, Inflammation and Sonic Hedgehog Pathway in Rats." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 3, pp. 1129-40, (2016) (PubMed).
Target

SMO (Smoothened Homolog (Drosophila) (SMO))

Andere Bezeichnung

Smoothened homolog

Hintergrund

Synonyms: Gx, SMOH, FZD11, Smoothened homolog, SMO, Protein Gx
Background: G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.

Gen-ID

6608

UniProt

Q99835

Pathways

Hedgehog Signalweg