CRHR1 Antikörper

Produktnummer ABIN680758

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CRHR1 in WB, IF (p) und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 1 Publikation erwähnt.

Kurzübersicht für CRHR1 Antikörper (ABIN680758)

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CRHR1 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRHR1/CRFR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Referenzen für anti-CRHR1 Antikörper (ABIN680758)

Zhu, Xia, Han, Shao, Jing, Fan, Liu, Diao, Lv, Sun: "Xiao Yao San Improves Depressive-Like Behavior in Rats through Modulation of ?-Arrestin 2-Mediated Pathways in Hippocampus." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 902516, (2014) (PubMed).

Details zu CRHR1

Target: CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))

Andere Bezeichnung: CRHR1

Hintergrund:

Synonyms: Corticotropin releasing hormone receptor variant 1h,CRF-RI, CRF 1, CRF R, CRF1, CRFR1, CRH R1h, CRF-R1, CRHR 1, CRHR, CRHR1, CRHR1f, Releasing hormone receptor 1, Seven transmembrane helix receptor, corticotropin releasing hormone receptor 1, Crhr1, Crhr, MGC124237, MGC124240, CRF-R, CRF-R-1, CRF-R1, CRFR-1, CRH-R-1, CRH-R1, CRH-R1h, CRHR, CRHR1L, CRFR1_HUMAN.

Background: This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.

Molekulargewicht: 48kDa

Gen-ID: 1394

Pathways: Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity