CD44 Antikörper (Exon v10) (PE-Cy7)

Produktnummer ABIN680606

Der Kaninchen Polyklonal Anti-CD44-Antikörper wurde für IF (p) validiert. Er ist geeignet, CD44 in Proben von Human, Maus, Ratte, Hund und Schwein zu detektieren.

Kurzübersicht für CD44 Antikörper (Exon v10) (PE-Cy7) (ABIN680606)

Target: CD44

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD44 Antikörper ist konjugiert mit PE-Cy7

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CD44 Antikörper (PE-Cy7)

Bindungsspezifität: Exon v10

Spezifität: Excitation / Emission Wavelengths: 480,565,743nm/767nm

Aufreinigung: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human CD44v10
Please inquire for sequence information.

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1mg/1ml

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu CD44

Target: CD44

Andere Bezeichnung: CD44

Hintergrund: CD44 is a receptor for hyaluronic acid (HA). It mediates cell-cell and cell-matrix interactions through its affinity for HA and possibly also through its affinity for other ligands such as osteopontin collagens and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration tumor growth and progression. Also involved in lymphocyte activation recirculation and homing and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Synonym: ECMR III, Epican, Heparan sulfate proteoglycan, HUTCH I, Hyaluronate receptor, PGP 1, CD44 antigen, CD44 molecule, CDw44, ECMR III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, PGP 1, Phagocytic glycoprotein I.

Molekulargewicht: 82kDa

Gen-ID: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling