CYLD Antikörper (N-Term)
Kurzübersicht für CYLD Antikörper (N-Term) (ABIN6756791)
Target
Alle CYLD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - N-Term
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Spezifität
 - Human CYLD
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Aufreinigung
 - Protein A purified
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Immunogen
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                        A recombinant protein fragment from the N-terminal region of human CYLD.
Type of Immunogen: Recombinant protein - 
                                            
Isotyp
 - IgG
 
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Applikationshinweise
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                        Approved: WB (2 - 5 μg/mL)
Usage: CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling. - 
                                            
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - Lot specific
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Buffer
 - PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - avoid freeze thaw cycles
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C. Avoid freeze-thaw cycles.
 
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- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Andere Bezeichnung
 - CYLD
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Hintergrund
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                        Name/Gene ID: CYLD
Synonyms: CYLD, CDMT, Deubiquitinating enzyme CYLD, CYLDI, EAC, HSPC057, MFT1, MFT, SBS, TEM, BRSS, Ubiquitin thiolesterase CYLD, USPL2, CYLD1, KIAA0849, Ubiquitin thioesterase CYLD - 
                                            
Gen-ID
 - 1540
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Pathways
 - Apoptose, Activation of Innate immune Response
 
Target
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