TRKB Antikörper (AA 466-515)

Produktnummer ABIN6746328

Dieses Anti-TRKB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRKB in WB. Geeignet für Human, Affe, Kaninchen, Rind (Kuh) und Pferd. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für TRKB Antikörper (AA 466-515) (ABIN6746328)

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Reaktivität: Human, Affe, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRKB Antikörper

Bindungsspezifität: AA 466-515

Spezifität: Human NTRK2 / TRKB

Homologie: Percent identity by BLAST analysis: Human, Rabbit, Horse (100%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa466-515 of human NTRK2 (Q8WXJ5, NP_001018075). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Panda, Bovine, Rabbit, Horse (100%), Bat (87%), Galago (81%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-TRKB Antikörper (ABIN6746328)

Ktistaki, Talianidis: "Modulation of hepatic gene expression by hepatocyte nuclear factor 1." in: Science (New York, N.Y.), Vol. 277, Issue 5322, pp. 109-12, (1997) (PubMed).

Kritis, Ktistaki, Barda, Zannis, Talianidis: "An indirect negative autoregulatory mechanism involved in hepatocyte nuclear factor-1 gene expression." in: Nucleic acids research, Vol. 21, Issue 25, pp. 5882-9, (1994) (PubMed).

Kuo, Conley, Hsieh, Francke, Crabtree: "Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 24, pp. 9838-42, (1991) (PubMed).

Frain, Swart, Monaci, Nicosia, Stämpfli, Frank, Cortese: "The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain." in: Cell, Vol. 59, Issue 1, pp. 145-57, (1989) (PubMed).

Details zu TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Andere Bezeichnung: NTRK2 / TRKB

Hintergrund: Name/Gene ID: NTRK2
Subfamily: Trk/Ror
Family: Protein Kinase

Synonyms: NTRK2, gp145-TrkB, Trk-B, TRKB, Tropomyosin-related kinase B, TrkB tyrosine kinase, Tyrosine kinase receptor B

Gen-ID: 4915

NCBI Accession: NP_001018075

UniProt: Q16620

Pathways: RTK Signalweg, Neurotrophin Signalübertragung, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport