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CD40 Ligand Antikörper (AA 31-150)

Name: CD40 Ligand Antikörper (AA 31-150)
SKU: ABIN674439
Price: 384.62 EUR
Availability: InStock

CD40LG Reaktivität: Human, Maus, Ratte WB, FACS, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Rat spleen cells probed with Rabbit Anti-CD40L Polyclonal Antibody Alexa Fluor 488 Conjugated Secondary Antibody. (CD40 Ligand Antikörper (AA 31-150))

FACS

U937 cells probed with Rabbit Anti-CD40L Polyclonal Antibody (ABIN674439) at 1:100 for 40 minutes followed by incubation with Goat Anti-Rabbit IgG PE conjugated secondary at 1:100 (green) for 40 minutes compared to control cells (blue). (CD40 Ligand Antikörper (AA 31-150))

FACS

2 Abbildungen

(2 Referenzen)

Produktnummer ABIN674439

Datenblatt (PDF)

Target Alle CD40 Ligand (CD40LG) Antikörper anzeigen

CD40 Ligand (CD40LG)
Bindungsspezifität
15

10

8

7

6

4

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 31-150
Reaktivität
156

81

33

9

8

6

5

3

2

2

2

2

2

2

1

1

1
Human, Maus, Ratte
Wirt
92

76

25

12

11

2
Kaninchen
Passende Sekundärantikörper
Klonalität
127

86

4
Polyklonal
Konjugat
110

23

21

14

9

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Ligand Antikörper ist unkonjugiert
Applikation
119

100

57

49

40

29

22

18

15

13

12

12

7

6

4

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Human, Maus, Ratte

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human CD40L/CD154

Isotyp

IgG

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CD40LG Reaktivität: Maus FACS Wirt: Armenischer Hamster Monoclonal MR-1 FITC

anti-CD40 Ligand (CD40LG) (AA 33-62), (N-Term) antibody
CD40LG Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB19150 unconjugated

anti-CD40 Ligand (CD40LG) (AA 79-129) antibody
CD40LG Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 33-62) antibody
CD40LG Reaktivität: Human WB, FACS, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

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CD40LG Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) antibody (PE)
CD40LG Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal 24-31 PE

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG Reaktivität: Human FACS, ELISA Wirt: Maus Monoclonal 8H10F5 unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Zhang, Song, Shu, Li, Wu, Wang, Chen, Chang, Wu, Zhang, Wei: "BAFF upregulates CD28/B7 and CD40/CD154 expression and promotes mouse T and B cell interaction in vitro via BAFF receptor." in: Acta pharmacologica Sinica, Vol. 37, Issue 8, pp. 1101-9, (2016) (PubMed).

Rui-Kai, Jian: "Effects of xinfeng capsules on expression of platelet granule membrane protein 140 and platelet cluster of differentiation 40 ligand in peripheral blood of adjuvant arthritis rats." in: International journal of rheumatology, Vol. 2012, pp. 139696, (2012) (PubMed).
Target

CD40 Ligand (CD40LG)

Andere Bezeichnung

CD40L/CD154 (CD40LG Produkte)

Hintergrund

Synonyms: IGM, IMD3, TRAP, gp39, CD154, CD4L, HIGM1, T-BAM, TNFSF5, hCD4L, CD4 ligand, CD4-L, T-cell antigen Gp39, TNF-related activation protein, Tumor necrosis factor ligand superfamily member 5, CD4LG
Background: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.

Gen-ID

959

UniProt

P29965

Pathways

NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints