Presenilin 1 Antikörper (Val293)
Kurzübersicht für Presenilin 1 Antikörper (Val293) (ABIN6735742)
Target
Alle Presenilin 1 (PSEN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Val293
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Spezifität
- Detects endogenous levels of the carboxy-terminal fragment of presenilin 1 (~22kD). The antibody detects the full length protein (55kD) to a lesser extent. Species cross-reactivity: Human, rat and monkey. Species sequence homology: mouse 100 % .
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Synthetic peptide (KLH coupled) corresponding to residues around valine 293 of human presenilin 1.
Type of Immunogen: Synthetic peptide -
Isotyp
- IgG
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Applikationshinweise
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Approved: ELISA, IP (1:100), WB (1:500)
Usage: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:500. Immunoprecipitation: 1:100. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Presenilin 1 (PSEN1)
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Andere Bezeichnung
- PSEN1 / Presenilin 1
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Hintergrund
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Name/Gene ID: PSEN1
Subfamily: Aspartic A22A
Family: protease
Synonyms: PSEN1, AD3, Alzheimer disease 3, FAD, Protein S182, PS1, S182, PS-1, PSNL1, Presenilin 1, Presenilin-1 -
Gen-ID
- 5663
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UniProt
- P49768
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Pathways
- Notch Signalweg, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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