FASL Antikörper (C-Term)

Produktnummer ABIN6735258

Dieses Anti-FASL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FASL in WB und ELISA. Geeignet für Human.

Kurzübersicht für FASL Antikörper (C-Term) (ABIN6735258)

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FASL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FASL Antikörper

Bindungsspezifität: C-Term

Spezifität: Sequence is 94 % conserved in mouse. It is poorly conserved in human FASL. 92 % homologous with rat and mouse FASL. Based upon the sequence homology data, anti human FASL should cross-react with the mouse/rat FASL.

Aufreinigung: Immunoaffinity purified

Immunogen: 13-aa peptide from human FASL near the C terminus.

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (0.5 - 1 μg/mL), WB (1:1000 - 1:5000)

Usage: Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000 (ECL). We recommend the use of 0.5-1 % milk in diluents used for primary antibody and secondary antibody-enzyme conjugates to suppress background. Rat, mouse and human FASL have 278, 279, and 281aa residues, respectively (Calculated MW of ~32kD). Western blot of the oocyte has detected a specific 31-kD band. A 40kD FASL has been detected in mouse T cells. An alternate detecting reagent, mFAS-Fc also detected a cell surface protein of about 40kD. ELISA: 0.5-1 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 100 mM Tris,  pH 7.5, 0.2 % BSA, 40 % glycerol.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu FASL

Target: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Andere Bezeichnung: FASLG / FASL / Fas Ligand

Hintergrund: Name/Gene ID: FASLG
Family: TNF

Synonyms: FASLG, ALPS1B, Apoptosis antigen ligand, APTL, CD95L, CD95 ligand, CD178 antigen, CD95-L, Fas antigen ligand, Fas ligand, FASL, TNFSF6, APT1LG1, CD178

Gen-ID: 356

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity