TRAF1 Antikörper (AA 301-416) (Biotin)
Kurzübersicht für TRAF1 Antikörper (AA 301-416) (Biotin) (ABIN673466)
Target
Alle TRAF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-416
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Dog,Cow,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human TRAF1
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Isotyp
- IgG
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Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
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Andere Bezeichnung
- TRAF1
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Hintergrund
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Synonyms: EBI6, MGC:10353, TNF receptor-associated factor 1, Epstein-Barr virus-induced protein 6, TRAF1
Background: Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
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Gen-ID
- 7185
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UniProt
- Q13077
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Pathways
- NF-kappaB Signalweg, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization
Target
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