CD3 Antikörper (mFluor™450)
Kurzübersicht für CD3 Antikörper (mFluor™450) (ABIN6731073)
Target
Alle CD3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD3 mFluor™ 450 Antibody
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Produktmerkmale
- The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.
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Aufreinigung
- Purified
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Reinheit
- >95 %
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Immunogen
- Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
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Isotyp
- IgG1, kappa
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anti-CD3 (CD3) antibody
CD3 Reaktivität: Human, Maus, Ratte IHC, IF, WB Wirt: Kaninchen Polyclonal unconjugated
anti-CD3 (CD3) antibodyCD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro), ICC, MS Wirt: Maus Monoclonal UCHT1 unconjugated
anti-CD3 (CD3) antibodyCD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro), Func, MS Wirt: Maus Monoclonal UCHT1 unconjugated
anti-CD3 (CD3) antibodyCD3 Reaktivität: Human FACS, IP, Func, MS Wirt: Maus Monoclonal MEM-57 unconjugated
anti-CD3 (CD3) antibodyCD3 Reaktivität: Human FACS, IP, MS Wirt: Maus Monoclonal MEM-57 unconjugated
anti-CD3 (CD3) antibody (Biotin)CD3 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal UCHT1 Biotin
anti-CD3 (CD3) antibody (Biotin)CD3 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-57 Biotin
anti-CD3 (CD3) antibody (PerCP)CD3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal UCHT1 PerCP
anti-CD3 (CD3) antibody (APC)CD3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal UCHT1 APC
anti-CD3 (CD3) antibody (PE)CD3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal UCHT1 PE
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD3
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Andere Bezeichnung
- CD3
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Gen-ID
- 916
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NCBI Accession
- NM_000733
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UniProt
- P07766
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Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
Target
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