IL-10 Antikörper (FITC)

Produktnummer ABIN6728556

Dieses Anti-IL-10-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von IL-10 in ICFC. Geeignet für Maus.

Kurzübersicht für IL-10 Antikörper (FITC) (ABIN6728556)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-10 Antikörper ist konjugiert mit FITC

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: JES5-16E3

Produktdetails anti-IL-10 Antikörper (FITC)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: FITC Rat IgG2b, κ Isotype Control (ABIN7469858)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Details zu IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung: IL-10

Hintergrund: Interleukin-10,IL-10,Cytokine synthesis inhibitory factor,CSIF,L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80 % sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones, inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis, suppresses the delayed type hypersensitivity response, stimulates Th2 cell response (which results in elevated antibody production), and promotes mast cell proliferation in combination with IL-4.

Gen-ID: 16153

UniProt: P18893

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints