Galectin 3 Antikörper (AA 151-250)

Produktnummer ABIN672321

Dieses Anti-Galectin 3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Galectin 3 in ELISA, IHC (p), FACS, IF (cc), IF (p) und IHC (fro). Geeignet für Human und Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für Galectin 3 Antikörper (AA 151-250) (ABIN672321)

Target: Galectin 3 (LGALS3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Galectin 3 Antikörper

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Galectin 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Galectin 3 Antikörper (ABIN672321)

White, Roife, Gomer: "Galectin-3 Binding Protein Secreted by Breast Cancer Cells Inhibits Monocyte-Derived Fibrocyte Differentiation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 4, pp. 1858-67, (2015) (PubMed).

Lee, Bae, Choi, Park, Chun: "Molecular cloning and expression analysis of pig CD7." in: Veterinary research communications, Vol. 38, Issue 3, pp. 257-63, (2014) (PubMed).

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin 3

Substanzklasse: Chemical

Hintergrund:

Synonyms: L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2, Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3

Background: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Gen-ID: 3958

UniProt: P17931

Pathways: RTK Signalweg