DR4 Antikörper (AA 401-468)
Kurzübersicht für DR4 Antikörper (AA 401-468) (ABIN670581)
Target
Alle DR4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 401-468
- 
                                            Kreuzreaktivität
- Human
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human DR4
- 
                                            Isotyp
- IgG
 
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- 
    
- 
    - 
                                            Applikationshinweise
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            Haltbarkeit
- 12 months
 
- 
                                            
- 
    - DR4 (Drought-Repressed 4 Protein (DR4))
- 
                                            Andere Bezeichnung
- DR4
- 
                                            Hintergrund
- 
                        Synonyms: DR4, APO2, CD261, TRAILR1, TRAILR-1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, TNFRSF10A Background: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. 
- 
                                            Gen-ID
- 8797
- 
                                            UniProt
- O00220
- 
                                            Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
 Target
- 
                    
 
                                     
                                     
                                    