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KIT Ligand Antikörper (AA 151-250) (PE)

KITLG Reaktivität: Human, Maus, Ratte WB, FACS Wirt: Kaninchen Polyclonal PE

Produktnummer ABIN669946

Datenblatt (PDF)

Target Alle KIT Ligand (KITLG) Antikörper anzeigen

KIT Ligand (KITLG)
Bindungsspezifität
15

7

7

5

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 151-250
Reaktivität
109

55

33

5

4

2

2

2

2

2

1

1

1

1

1
Human, Maus, Ratte
Wirt
109

24

6

1
Kaninchen
Passende Sekundärantikörper
Klonalität
109

31
Polyklonal
Konjugat
71

15

7

6

4

3

3

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser KIT Ligand Antikörper ist konjugiert mit PE
Applikation
102

51

36

26

19

15

14

14

13

13

10

6

6

4

4

4

3

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

Kreuzreaktivität

Human, Maus, Ratte

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human SCF

Isotyp

IgG

Top Product

Discover our top product KITLG Primärantikörper
anti-KIT Ligand (KITLG) (AA 151-250) antibody
KITLG Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) antibody
KITLG Reaktivität: Human WB, ELISA, Neut Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) (AA 26-190) antibody
KITLG Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) (AA 244-273) antibody
KITLG Reaktivität: Human WB, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) (Middle Region) antibody
KITLG Reaktivität: Human, Maus, Ratte, Schwein, Hund, Rind (Kuh), Ziege, Pferd, Kaninchen, Schaf, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) (AA 180-229) antibody
KITLG Reaktivität: Human, Maus, Ratte, Schwein, Hund, Rind (Kuh), Ziege, Pferd, Kaninchen, Schaf, Huhn, Hamster, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) (Middle Region) antibody
KITLG Reaktivität: Human, Maus, Ratte, Hund WB Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) antibody
KITLG Reaktivität: Human, Maus, Ratte WB, IHC (p), ELISA (Capture) Wirt: Kaninchen Polyclonal unconjugated

anti-KIT Ligand (KITLG) (AA 201-234), (C-Term) antibody
KITLG Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB50736 unconjugated

anti-KIT Ligand (KITLG) (AA 1-245) antibody
KITLG Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

FCM 1:20-100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

KIT Ligand (KITLG)

Andere Bezeichnung

SCF (KITLG Produkte)

Hintergrund

Synonyms: SF, MGF, SCF, FPH2, KL-1, Kitl, SHEP7, Kit ligand, Mast cell growth factor, Stem cell factor, c-Kit ligand, KITLG
Background: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins.

Gen-ID

4254

UniProt

P21583

Pathways

RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung