Integrin beta 2 Antikörper (AA 701-770) (Cy7)

Produktnummer ABIN669417

Produktdetails anti-Integrin beta 2 Antikörper (Cy7)

Target: Integrin beta 2 (ITGB2)

Bindungsspezifität: AA 701-770

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin beta 2 Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin beta 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Andere Bezeichnung: CD18 (ITGB2 Produkte)

Synonyme: CD18 antikoerper, LAD antikoerper, LCAMB antikoerper, LFA-1 antikoerper, MAC-1 antikoerper, MF17 antikoerper, MFI7 antikoerper, 2E6 antikoerper, AI528527 antikoerper, Cd18 antikoerper, Lfa1 antikoerper, ITGB2 antikoerper, itgb2 antikoerper, itgb2-a antikoerper, itgb2-b antikoerper, integrin subunit beta 2 antikoerper, integrin beta 2 antikoerper, integrin subunit beta 2 S homeolog antikoerper, ITGB2 antikoerper, Itgb2 antikoerper, itgb2.S antikoerper

Hintergrund:

Synonyms: LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, ITGB2

Background: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.

Gen-ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation