GRIA2 Antikörper

Produktnummer ABIN6658246

Hersteller Produkt- Nr.: 612-401-d62

Der Kaninchen Polyklonal Anti-GRIA2-Antikörper wurde für WB validiert. Er ist geeignet, GRIA2 in Proben von Ratte zu detektieren.

Kurzübersicht für GRIA2 Antikörper (ABIN6658246)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRIA2 Antikörper

Hersteller Produkt- Nr.: 612-401-d62

Hersteller: Rockland

Verwendungszweck: GluR2 Antibody

Kreuzreaktivität (Details): Anti-GluR2 Antibody is directed against rat GluR2 protein.

Aufreinigung: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-GluR2 Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to GluR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Anti-GluR2 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to GluR2 protein in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Andere Bezeichnung: GluR2

Hintergrund:

Synonyms: Glutamate receptor 2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2

Background: GluR2 Antibody detects GluR2. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD. Therefore, GluR2 antibody is ideal for investigators involved in synapse plasticity study and in general in Neuroscience.

Gene Name: GRIA2

Gen-ID: 29627

UniProt: P19491

Pathways: PI3K-Akt Signalweg