Glutamate Receptor 1 Antikörper (N-Term)

Produktnummer ABIN6658217

Hersteller Produkt- Nr.: 200-301-d61

Dieses Anti-Glutamate Receptor 1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Glutamate Receptor 1 in WB. Geeignet für Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Glutamate Receptor 1 Antikörper (N-Term) (ABIN6658217)

Target: Glutamate Receptor 1 (GLUR1)

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutamate Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RH95

Produktdetails anti-Glutamate Receptor 1 Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 200-301-d61

Hersteller: Rockland

Verwendungszweck: GluR1 Antibody

Kreuzreaktivität (Details): Anti-GluR1 Monoclonal Antibody is directed against rat GluR1 protein.

Aufreinigung: The antibody was Protein G purified from cell culture supernatant.

Immunogen: Anti-GluR1 Monoclonal Antibody was produced by repeated immunizations with GluR1- Synthetic peptide corresponding to amino acid residues from the N-terminal region.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optional[Neutralization_Dilution]: 1:1000

Kommentare:

Suggested Applications: IF
Anti-GluR1 (Mouse) antibody has been tested by Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to GluR1 proteins in Western Blot in the appropriate cell lysate or extract.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Referenzen für anti-Glutamate Receptor 1 Antikörper (ABIN6658217)

Domínguez-Sala, Andreu-Cervera, Martín-Climent, Murcia-Ramón, Martínez, Geijo-Barrientos: "Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction." in: Brain structure & function, Vol. 227, Issue 5, pp. 1599-1614, (2022) (PubMed).

Details zu Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Andere Bezeichnung: GluR1

Hintergrund:

Synonyms: Glutamate receptor 1, GluR1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1,

Background: GluR1 Monoclonal Antibody detects GluR1. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. GluR1 monoclonal antibody is ideal for investigators involved in Neuroscience.

Gene Name: GRIA1

Gen-ID: 50592

UniProt: P19490

Pathways: PI3K-Akt Signalweg