HCN1 Antikörper (C-Term)

Produktnummer ABIN6658105

Produktdetails anti-HCN1 Antikörper

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-HCN1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with HCN1 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. No cross-reactivity against HCN2. Cross-reactivity with HCN1 from other sources has not been determined. Channels and Transporters research.

Immunogen:

Immunogen: HCN1 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to the C terminus region of rat HCN1.

Immunogen Type: Recombinant Protein

Klon: S70-28

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-HCN1 Antibody is suitable for use in WB, IP and IHC. Expect a band approximately ~100 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1-10 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu HCN1

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Andere Bezeichnung: HCN1 (HCN1 Produkte)

Synonyme: BCNG-1 antikoerper, BCNG1 antikoerper, HAC-2 antikoerper, Bcng1 antikoerper, C630013B14Rik antikoerper, HAC2 antikoerper, hyperpolarization activated cyclic nucleotide gated potassium channel 1 antikoerper, hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 antikoerper, hyperpolarization-activated, cyclic nucleotide-gated K+ 1 antikoerper, hcn1 antikoerper, HCN1 antikoerper, Hcn1 antikoerper

Hintergrund:

Synonyms: BCNG1, HAC2, potassium/sodium hyperpolarization activted cycli nucleotide gated channel 1

Background: Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulatons of cell excitability. Importantly, they contribute to spontaneous rhythmic activity in both the heart and brain.

Gene Name: Hcn1

Gen-ID: 84390

NCBI Accession: NP_445827

UniProt: Q9JKB0

Pathways: Asymmetric Protein Localization