HCN1 Antikörper (AA 778-910)

Produktnummer ABIN361763

Produktdetails anti-HCN1 Antikörper

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Bindungsspezifität: AA 778-910

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Antibody Array (AA)

Spezifität: Detects ~100 kDa. No cross-reactivity against HCN2.

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 778-910 (C terminus) of rat HCN1

Klon: S70

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN361763 was sufficient for detection of HCN1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu HCN1

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Andere Bezeichnung: HCN1 (HCN1 Produkte)

Synonyme: BCNG-1 antikoerper, BCNG1 antikoerper, HAC-2 antikoerper, Bcng1 antikoerper, C630013B14Rik antikoerper, HAC2 antikoerper, hyperpolarization activated cyclic nucleotide gated potassium channel 1 antikoerper, hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 antikoerper, hyperpolarization-activated, cyclic nucleotide-gated K+ 1 antikoerper, hcn1 antikoerper, HCN1 antikoerper, Hcn1 antikoerper

Hintergrund: Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, play a crucial role in the regulatons of cell excitability. Importantly, they contribute to spontaneous rhythmic activity in both the heart and brain (1).

Gen-ID: 84390

NCBI Accession: NP_445827

UniProt: Q9JKB0

Pathways: Asymmetric Protein Localization