Tryptophan Hydroxylase 1 Antikörper

Produktnummer ABIN6658049

Hersteller Produkt- Nr.: 600-601-c96

Dieses Anti-Tryptophan Hydroxylase 1-Antikörper ist ein Schaf Polyklonal-Antikörper zur Detektion von Tryptophan Hydroxylase 1 in WB und IHC. Geeignet für Kaninchen.

Kurzübersicht für Tryptophan Hydroxylase 1 Antikörper (ABIN6658049)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reaktivität: Kaninchen

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Tryptophan Hydroxylase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Tryptophan Hydroxylase 1 Antikörper

Hersteller Produkt- Nr.: 600-601-c96

Hersteller: Rockland

Verwendungszweck: Tryptophan Hydroxylase Antibody

Kreuzreaktivität (Details): Anti-Tryptophan Hydroxylase antibody is directed against Tryptophan 5-hydroxylase 1.

Aufreinigung: Tryptophan Hydroxylase antibodies are affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Tryptophan Hydroxylase Antibody was produced in sheep by repeated immunizations with recombinant rabbit tryptophan hydroxylase, isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: 1:1000

Western_Blot_Dilution: 1:1000

Kommentare:

Anti-Tryptophan Hydroxylase (Sheep) antibody is tested for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to tryptophan hydroxylase protein in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Andere Bezeichnung: Tryptophan Hydroxylase

Hintergrund:

Synonyms: Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1

Background: Tryptophan Hydroxylase antibody detects Tryptophan Hydroxylase. TPH catalyzes the first step in the biosynthesis of serotonin and melatonin. Thus, expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis. Anti-Tryptophan Hydroxylase antibody is ideal for investigators involved in Cell Signaling and Neuroscience research.

Gene Name: TPH1

Gen-ID: 100101558

NCBI Accession: NP_001093425

UniProt: P17290

Pathways: Feeding Behaviour