Tryptophan Hydroxylase 1 Antikörper (AA 345-444)
Kurzübersicht für Tryptophan Hydroxylase 1 Antikörper (AA 345-444) (ABIN3022155)
Target
Alle Tryptophan Hydroxylase 1 (TPH1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 345-444
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Sequenz
- LSGHAKVKPF DPKITCKQEC LITTFQDVYF VSESFEDAKE KMREFTKTIK RPFGVKYNPY TRSIQILKDT KSITSAMNEL QHDLDVVSDA LAKVSRKPSI
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 345-444 of human TPH1 (NP_004170.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Tryptophan Hydroxylase 1 (TPH1)
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Andere Bezeichnung
- TPH1
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Hintergrund
- This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.,TPH1,TPRH,TRPH,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,TPH1
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Molekulargewicht
- 50 kDa/53 kDa
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Gen-ID
- 7166
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UniProt
- P17752
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Pathways
- Feeding Behaviour
Target
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