Tryptophan Hydroxylase 1 Antikörper (AA 26-75)

Produktnummer ABIN1532659

Der Kaninchen Polyklonal anti-Tryptophan Hydroxylase 1 Antikörper wird verwendet zum Nachweis von Tryptophan Hydroxylase 1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für Tryptophan Hydroxylase 1 Antikörper (AA 26-75) (ABIN1532659)

Target: Tryptophan Hydroxylase 1 (TPH1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tryptophan Hydroxylase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Tryptophan Hydroxylase 1 Antikörper

Bindungsspezifität: AA 26-75

Verwendungszweck: TPH1 Antibody

Spezifität: TPH1 Polyclonal Antibody detects endogenous levels of TPH1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Tryptophan Hydroxylase. AA range:26-75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Andere Bezeichnung: Tryptophan Hydroxylase

Hintergrund:

Synonyms: TPH1, TPH, TPRH, TRPH, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1

Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009],

Gene Name: TPH1

Protein Name: Tryptophan 5-hydroxylase 1

Molekulargewicht: 50 kDa

Gen-ID: 7166

OMIM: 191060

UniProt: P17752

Pathways: Feeding Behaviour