CD40 Ligand Antikörper (PE)

Produktnummer ABIN6657774

Hersteller Produkt- Nr.: 200-b08-n91

Dieses Hamster Monoklonal-Antikörper erkennt spezifisch CD40 Ligand in FACS und IHC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD40 Ligand Antikörper (PE) (ABIN6657774)

Target: CD40 Ligand (CD40LG)

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD40 Ligand Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Klon: MR1

Produktdetails anti-CD40 Ligand Antikörper (PE)

Hersteller Produkt- Nr.: 200-b08-n91

Hersteller: Rockland

Verwendungszweck: CD154 (CD40L) Phycoerythrin Antibody

Kreuzreaktivität (Details): Cross reactivity with CD154 from other sources has not been tested.

Aufreinigung: Phycoerythrin conjugated CD154 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD154.

Sterilität: Sterile filtered

Immunogen: Anti-CD154 Antibody (Monoclonal) was produced by repeated immunizations with Activated mouse Th1 clone D1.6.

Isotyp: IgG

Labeling Ratio: 1-2

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry_Dilution: User Optimized

Flow_Cytometry_Dilution: 10 μL/10^6 cells (0.1 μg)

Kommentare:

Anti-CD154 is tested for FLOW and useful for Immunohistochemistry using mouse spleen cells, or an appropriate cell type (where indicated). Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Haltbarkeit: 6 months

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: CD154(CD0L)

Hintergrund:

Synonyms: CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD154, Cd40lg, Cd40l, Tnfsf5

Background: CD154 is a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4+ lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation. The MR1 antibody has been reported to inhibit the activation of T and B lymphocytes in vitro and antigen-specific lymphocyte responses in vivo.

Gene Name: Cd40lg

Gen-ID: 21947

NCBI Accession: NP_035746

UniProt: P27548

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints