SPTAN1 Antikörper

Produktnummer ABIN6656378

Hersteller Produkt- Nr.: 100-401-w92

Dieses Anti-SPTAN1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPTAN1 in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für SPTAN1 Antikörper (ABIN6656378)

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-SPTAN1 Antikörper

Hersteller Produkt- Nr.: 100-401-w92

Hersteller: Rockland

Verwendungszweck: Alpha II Spectrin Antibody

Aufreinigung: Anti-Alpha II Spectrin Antibody was purified in a neat serum.

Sterilität: Sterile filtered

Immunogen: Anti-Alpha II Spectrin Antibody was produced in rabbits by repeated immunizations with a recombinant construct containing the 7th, 8th, 9th repeats of human alpha II spectrin expressed in and purified from E. coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:50,000

Immunohistochemistry_Dilution: 1:500-1:1000

Western_Blot_Dilution: 1:3000

Other: ICC: 1:500-1:1000

Kommentare:

Anti-Alpha II Spectrin Antibody is stored as a neat serum. It is tested for Western Blot, immunohistochemistry, and immunocytochemistry. Expect a band at approximately ~240 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu SPTAN1

Target: SPTAN1 (Spectrin alpha Chain, Brain (SPTAN1))

Andere Bezeichnung: Alpha II Spectrin

Hintergrund:

Synonyms: Spectrin alpha chain non-erythrocytic 1, Fodrin alpha chain, Spectrin nonerythroid alpha subunit

Background: The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (α1 and α2) and five beta genes (β1-β5). Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001). Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis. Alpha II Spectrin Antibody is ideal for researchers interested in cell cycle research.

Gene Name: SPTAN1

Gen-ID: 6709

NCBI Accession: NP_001123910

UniProt: Q13813

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization