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TLR8 Antikörper

This anti-TLR8 antibody (ABIN6655316) is a Mouse Monoclonal antibody detecting TLR8 in WB, IHC, IF, FACS, DB. Suitable for Human.
Rockland
Produktnummer ABIN6655316
Hersteller Produkt- Nr.: 200-301-i30

Kurzübersicht für TLR8 Antikörper (ABIN6655316)

Target

Alle TLR8 Antikörper anzeigen
TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität

  • 84
  • 46
  • 36
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 82
  • 13
  • 2
  • 1
Maus

Klonalität

  • 84
  • 14
Monoklonal

Konjugat

  • 41
  • 10
  • 9
  • 8
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TLR8 Antikörper ist unkonjugiert

Applikation

  • 72
  • 44
  • 26
  • 15
  • 13
  • 13
  • 11
  • 10
  • 8
  • 7
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Dot Blot (DB)

Klon

44C143
  • Hersteller Produkt- Nr.

    200-301-i30

    Hersteller

    Rockland

    Verwendungszweck

    TLR8 Antibody

    Kreuzreaktivität (Details)

    A BLAST analysis was used to suggest cross-reactivity with Anti-TLR8 from human and mouse based on 100 % homology with the immunizing sequence.

    Aufreinigung

    Anti-TLR8 Antibody was purified by Protein G chromatography.

    Immunogen

    TLR8 Antibody was produced in mice prepared by repeated immunizations with amino acids corresponding to an internal sequence of human TLR8 protein.

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Immunohistochemistry_Dilution: 5 μg/mL

    Flow_Cytometry_Dilution: 0.5-1 μg/10^6 cells

    Western_Blot_Dilution: 1-3 μg/mL

    Kommentare

    Anti-TLR8 Antibody is tested for use in WB, DB, Flow, Flow-CS, Flow-IC, ICC/IF, IHC, and IHC-P. Expect a band approximately 121kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Target

    TLR8 (Toll-Like Receptor 8 (TLR8))

    Andere Bezeichnung

    TLR8

    Hintergrund

    Synonyms: Toll-like receptor 8

    Background: Anti-TLR8 CD288 Antibody detects human TLR8. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa. Anti-TLR8 CD288 Antibody is ideal for investigators involved in cytokines and growth factor research.

    Gene Name: TLR8

    Gen-ID

    51311

    NCBI Accession

    NP_619542

    UniProt

    Q9NR97

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades
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