HIST1H2AB Antikörper (C-Term)

Produktnummer ABIN6655250

Hersteller Produkt- Nr.: 600-401-x48

Dieses Anti-HIST1H2AB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HIST1H2AB in WB, ELISA, IF, ChIP und FM. Geeignet für Human.

Kurzübersicht für HIST1H2AB Antikörper (C-Term) (ABIN6655250)

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIST1H2AB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Fluorescence Microscopy (FM)

Produktdetails anti-HIST1H2AB Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 600-401-x48

Hersteller: Rockland

Verwendungszweck: Histone H2A pan Antibody

Kreuzreaktivität (Details): Cross reactivity with other species was not tested.

Aufreinigung: Anti-Histone H2A pan Antibody was purified by affinity purification.

Sterilität: Sterile filtered

Immunogen: Anti-Histone H2A pan Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing a sequence from the C-terminus of histone H2A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ChIP_Dilution: 1-2 μg per IP

ELISA_Dilution: 1:100 - 1:1,000

IF_Microscopy_Dilution: 1:500

Western_Blot_Dilution: 1:2,000

Other: Dot Blot: 1:20,000

Kommentare:

Anti-Histone H2A pan Antibody has been tested by Chromatin Immunoprecipitation, western blot, immunofluorescence, and ELISA. Specific conditions for reactivity should be optimized by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Konservierungsmittel: ProClin, Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu HIST1H2AB

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Andere Bezeichnung: HIST1H2AB

Hintergrund:

Synonyms: Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, H2AFM, HIST1H2AE, H2AFA

Background: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a internal role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes. Anti-Histone H2A pan Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics.

Gene Name: HIST1H2AB

Gen-ID: 8329

NCBI Accession: NP_003500

UniProt: P0C0S8

Pathways: Telomere Maintenance