Histone Cluster 1, H2ab (HIST1H2AB) (AA 12-40), (N-Term) Antikörper

Details zu Produkt Nr. ABIN656986, Anbieter: Anmelden zum Anzeigen
Antigen
  • H2A/m
  • H2AFM
  • H2A.1
  • H2a-53
  • histone cluster 1 H2A family member b
  • histone cluster 1, H2ab
  • HIST1H2AB
  • Hist1h2ab
Epitop
AA 12-40, N-Term
20
14
14
5
3
2
1
Reaktivität
Human
44
2
2
Wirt
Kaninchen
44
Klonalität (Klon)
Polyklonal ()
Konjugat
Unkonjugiert
5
5
4
4
4
4
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
42
35
19
15
2
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This HIST1H2AB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 AA from the N-terminal region of human HIST1H2AB.
Klon RB32983
Isotyp Ig Fraction
Spezifität This HIST1H2AB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human HIST1H2AB.
Homologie Cow (Bovine),Chicken,Mouse (Murine),Monkey,Rat (Rattus),Xenopus laevis,Zebrafish
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung HIST1H2AB (HIST1H2AB Antibody Abstract)
Hintergrund Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H2A type 1-B/E,HIST1H2AB,H2AFM
Molekulargewicht 14135 DA
Gen-ID 8335, 3012
NCBI Accession NP_066390, NP_003504
UniProt P04908
Forschungsgebiet Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Cell Structure
Pathways Telomere Maintenance
Applikationshinweise WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung HIST1H2AB Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit 6 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Histone Cluster 1, H2ab (HIST1H2AB) (AA 12-40), (N-Term) antibody (ABIN656986) HIST1H2AB Antibody (N-term) (ABIN656986) immunohistochemistry analysis in formalin fi...
Allgemeine Veröffentlichungen Cao, Tsukada, Zhang: "Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing." in: Molecular cell, Vol. 20, Issue 6, pp. 845-54, 2005 (PubMed).

Hagiwara, Hidaka, Yamada: "Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes." in: Biochemistry, Vol. 44, Issue 15, pp. 5827-34, 2005 (PubMed).

Andersen, Lam, Leung, Ong, Lyon, Lamond, Mann: "Nucleolar proteome dynamics." in: Nature, Vol. 433, Issue 7021, pp. 77-83, 2005 (PubMed).

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