CD40 Ligand Antikörper (APC)

Produktnummer ABIN6655106

Hersteller Produkt- Nr.: 200-326-n76

Dieses Anti-CD40 Ligand-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD40 Ligand in FACS und FM. Geeignet für Human.

Kurzübersicht für CD40 Ligand Antikörper (APC) (ABIN6655106)

Target: CD40 Ligand (CD40LG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD40 Ligand Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS), Fluorescence Microscopy (FM)

Klon: 24-31

Produktdetails anti-CD40 Ligand Antikörper (APC)

Hersteller Produkt- Nr.: 200-326-n76

Hersteller: Rockland

Verwendungszweck: CD154 (CD40L) Allophycocyanin Antibody

Kreuzreaktivität (Details): Reactivity is observed against human CD154.

Aufreinigung: Allophycocyanin conjugated CD154 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD154.

Sterilität: Sterile filtered

Immunogen: Anti-CD154 Antibody (Monoclonal) was produced by repeated immunizations with CD154 antigen.

Isotyp: IgG1 kappa

Labeling Ratio: 1-2

Anwendungsinformationen

Applikationshinweise:

Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells

IF_Microscopy_Dilution: User Optimized

Kommentare:

Anti-CD154 is tested for Flow Cytometry and useful in Immunofluorescence. Researchers should determine optimal titers for applications that are not stated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.2 % BSA (w/v)

Preservative: 0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Haltbarkeit: 6 months

Details zu CD40 Ligand

Target: CD40 Ligand (CD40LG)

Andere Bezeichnung: CD154 (CD40L)

Hintergrund:

Synonyms: CD40 ligand, CD40-L, T-cell antigen Gp39, TNF-related activation protein, TRAP, Tumor necrosis factor ligand superfamily member 5, CD40LG, CD40L, TNFSF5, TRAP

Background: CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.

Gene Name: CD40LG

Gen-ID: 959

NCBI Accession: NP_000065

UniProt: P29965

Pathways: NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints