PSA
Reaktivität: Human
IHC (p)
Wirt: Kaninchen
Monoclonal
L15-V
unconjugated
Applikationshinweise
The optimal dilution of the recombinant PSA antibody for each application should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the recombinant PSA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Target
Prostate Specific Antigen (PSA)
Andere Bezeichnung
PSA / Prostate Specific Antigen
Hintergrund
Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with mAb < a href=../tds/psa-antibody-prostate-specific-antigen-a67-be3-v2003>A67-B/E3 for PSA tests.