IL36A/IL1F6 Antikörper (AA 6-151)

Produktnummer ABIN6654183

Produktdetails anti-IL36A/IL1F6 Antikörper

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Bindungsspezifität: AA 6-151

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL36A/IL1F6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: Human IL-36 alpha recombinant protein (amino acids K6-D151) was used as the immunogen for the IL36A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL36A antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,ELISA (capture): 1-5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the IL36A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IL36A/IL1F6

Target: IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))

Andere Bezeichnung: IL-36 alpha / IL-1F6 (IL1F6 Produkte)

Synonyme: Il1f6 antikoerper, Fil1 antikoerper, IL-1H1 antikoerper, IL1RP2 antikoerper, Il1f9 antikoerper, Il36a antikoerper, FIL1 antikoerper, FIL1(EPSILON) antikoerper, FIL1E antikoerper, IL-1F6 antikoerper, IL1(EPSILON) antikoerper, IL1F6 antikoerper, interleukin 36, alpha antikoerper, interleukin 1 family, member 6 (epsilon) antikoerper, interleukin 1 family, member 6 antikoerper, interleukin 36 alpha antikoerper, Il36a antikoerper, IL1F6 antikoerper, IL36A antikoerper, Il1f6 antikoerper

Hintergrund: Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.

UniProt: Q9UHA7

Pathways: Cancer Immune Checkpoints