APEX1 Antikörper (acLys6)

Produktnummer ABIN6579711

Dieses Anti-APEX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von APEX1 in WB und ELISA. Geeignet für Human.

Kurzübersicht für APEX1 Antikörper (acLys6) (ABIN6579711)

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APEX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-APEX1 Antikörper

Bindungsspezifität: AA 1-50, acLys6

Spezifität:

APE1 (Acetyl-Lys6) Antibody detects endogenous levels of APE1 protein only when acetylated at Lys6.

Acetylation: H:K6

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.

Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human APE1 around the Acetylation site of Lys6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 ELISA: 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Details zu APEX1

Target: APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))

Andere Bezeichnung: APE1

Hintergrund:

Synonyms: APEX1, APE, APE1, APEX, APX, HAP1, REF1, DNA-(apurinic or apyrimidinic site) lyase, APEX nuclease, APEN, Apurinic-apyrimidinic endonuclease 1, AP endonuclease 1, APE-1, REF-1, Redox factor-1

NCBI Gene Symbol: APEX1

Molekulargewicht: 35 kDa

Gen-ID: 328

OMIM: 107748

UniProt: P27695

Pathways: DNA Reparatur, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus