NADPH Oxidase 4 Antikörper (N-Term)

Produktnummer ABIN657946

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NADPH Oxidase 4 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NADPH Oxidase 4 Antikörper (N-Term) (ABIN657946)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB34043

Produktdetails anti-NADPH Oxidase 4 Antikörper

Bindungsspezifität: AA 124-153, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NOX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the N-terminal region of human NOX4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: NOX4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 66932

Gen-ID: 50507

NCBI Accession: NP_001137308, NP_058627

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration