TLR8 Antikörper (AA 434-463)

Produktnummer ABIN657933

Dieses Anti-TLR8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR8 in WB und IHC (p). Geeignet für Human.

Kurzübersicht für TLR8 Antikörper (AA 434-463) (ABIN657933)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB33953

Produktdetails anti-TLR8 Antikörper

Bindungsspezifität: AA 434-463

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-463 amino acids from the Central region of human TLR8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TLR8 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Andere Bezeichnung: TLR8

Hintergrund: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Molekulargewicht: 119828

Gen-ID: 51311

NCBI Accession: NP_619542

UniProt: Q9NR97

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades