K-RAS Antikörper (AA 150-189)

Produktnummer ABIN6579257

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch K-RAS in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für K-RAS Antikörper (AA 150-189) (ABIN6579257)

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser K-RAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-K-RAS Antikörper

Bindungsspezifität: AA 150-189

Verwendungszweck: K-Ras Antibody

Spezifität: K-Ras Polyclonal Antibody detects endogenous levels of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-189

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung: KRAS

Hintergrund:

Synonyms: GTPase KRas (K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]

Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],

Gene Name: KRAS

Protein Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Molekulargewicht: 21 kDa

Gen-ID: 3845

OMIM: 190070

UniProt: P01116