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RANGAP1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-RANGAP1-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, RANGAP1 in Proben von Human zu detektieren.
Produktnummer ABIN657698

Kurzübersicht für RANGAP1 Antikörper (N-Term) (ABIN657698)

Target

Alle RANGAP1 Antikörper anzeigen
RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Reaktivität

  • 50
  • 27
  • 27
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 41
  • 6
  • 2
  • 1
Kaninchen

Klonalität

  • 37
  • 13
Polyklonal

Konjugat

  • 31
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser RANGAP1 Antikörper ist unkonjugiert

Applikation

  • 30
  • 22
  • 15
  • 14
  • 5
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB33892
  • Bindungsspezifität

    • 8
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-49, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    RANGAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

    Haltbarkeit

    6 months
  • Target

    RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

    Andere Bezeichnung

    RANGAP1

    Hintergrund

    RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

    Molekulargewicht

    63542

    Gen-ID

    5905

    NCBI Accession

    NP_001265580, NP_002874

    UniProt

    P46060

    Pathways

    M Phase, Protein targeting to Nucleus
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