Mre11 Antikörper (AA 182-582)

Produktnummer ABIN190284

Dieses Anti-Mre11-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Mre11 in WB, ELISA, IP, IHC (p), IF/ICC, Func und PLA. Geeignet für Human.

Kurzübersicht für Mre11 Antikörper (AA 182-582) (ABIN190284)

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mre11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (fixed cells) (IF/ICC), Functional Studies (Func), Proximity Ligation Assay (PLA)

Klon: 12D7

Produktdetails anti-Mre11 Antikörper

Bindungsspezifität: AA 182-582

Verwendungszweck: Anti-Mre11 Mouse Monoclonal Antibody

Spezifität: This antibody recognizes human, mouse, and rat Mre11.

Kreuzreaktivität: Human

Immunogen: GST fusion protein corresponding to aa 182-582 of Mre11.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: Use at 0.5-2 μg/mL. A band of ~80 kDa is detected. Detection of Mre11 in 30 μg of whole cell extracts.
Immunofluorescence: use at 1-5 μg/mL. Detection of Mre11 in HeLa cells fixed in 4 % paraformaldehyde for 15 minutes.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C to-70°C. Store as concentrated solution in appropriate aliquots to avoid multiple freeze-thaw cycles.

Details zu Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Andere Bezeichnung: MRE11

Hintergrund: Double-strand break repair protein MRE11,Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA rPubMed:10888888, PubMed:11741547, PubMed:15064416, PubMed:29670289, PubMed:30612738, PubMed:9590181, PubMed:9705271}.,Nucleus, Chromosome, telomere, Chromosome,EC 3.1.-.-, Double-strand break repair protein MRE11A, Meiotic recombination 11 homolog 1, MRE11 homolog 1, Meiotic recombination 11 homolog A, MRE11 homolog A

UniProt: P49959

Pathways: DNA Reparatur