Fibulin 5 Antikörper (FBLN5)

Details for Product anti-FBLN5 Antibody No. ABIN6572097
Antigen
  • zgc:103575
  • FBLN5
  • MGC108414
  • Fibulin-5
  • DKFZp469K0327
  • ADCL2
  • ARCL1A
  • ARMD3
  • DANCE
  • EVEC
  • FIBL-5
  • UP50
  • A55
  • fibulin 5
  • fbln5
  • FBLN5
  • Fbln5
Reaktivität
Human, Maus
129
56
42
2
1
Wirt
Kaninchen
100
34
7
Klonalität
Polyklonal
Konjugat
Dieser Fibulin 5 Antikörper ist unkonjugiert
13
6
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
Applikation
Western Blotting (WB)
117
77
40
14
13
7
6
6
3
2
2
1
1
Optionen
Immunogen Recombinant protein of human FBLN5
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere Fibulin 5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Fibulin 5 (FBLN5 Antibody Abstract)
Hintergrund

Synonyms: ADCL2,ARCL1A,ARMD3,Dance,Developmental arteries and neural crest EGF like protein,Developmental arteries and neural crest EGF-like protein,EVEC,Fbln5,FBLN5,FIBL 5,FIBL-5,Fibulin-5,FLJ90059,UP50,Urine p50 protein

Background: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Molekulargewicht

Observed_MW: 70kDa

Calculated_MW: 50kDa

Gen-ID 10516
UniProt Q9UBX5
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Fibulin 5 (FBLN5) antibody (ABIN6572097) Western blot analysis of extracts of various cell lines, using FBLN5 antibody.
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