Metabotropic Glutamate Receptor 5 Antikörper (Glutamate Receptor, Metabotropic 5)

Details for Product anti-GRM5 Antibody No. ABIN6572027
Antigen
  • GPRC1E
  • MGLUR5
  • mGlu5
  • mGluR5
  • mGlur5
  • 6430542K11Rik
  • AI850523
  • Glu5R
  • Gprc1e
  • mGluR5b
  • glutamate receptor, metabotropic 5
  • glutamate metabotropic receptor 5
  • GRM5
  • Grm5
Reaktivität
Human, Maus, Ratte (Rattus)
206
166
155
7
6
5
5
3
3
3
2
2
1
Wirt
Kaninchen
115
91
4
2
Klonalität
Polyklonal
Konjugat
Dieser Metabotropic Glutamate Receptor 5 Antikörper ist unkonjugiert
12
10
7
6
6
6
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Applikation
Western Blotting (WB)
175
112
82
68
57
39
37
22
13
5
4
3
2
1
Optionen
Immunogen Recombinant protein of human GRM5
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere Metabotropic Glutamate Receptor 5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung GRM5 (GRM5 Antibody Abstract)
Hintergrund

Synonyms: Glutamate receptor metabotropic 5,GPRC1E,Grm5,GRM5,Metabotropic glutamate receptor 5,Metabotropic glutamate receptor 5 variant F,Metabotropic glutamate receptor 5 variant G,Metabotropic glutamate receptor 5 variant H,mGlu5,mGluR5,PPP1R86,Protein phosphatase 1 regulatory subunit 86

Background: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

Molekulargewicht

Observed_MW: 132kDa

Calculated_MW: 105kDa/128kDa/132kDa

Gen-ID 2915
UniProt P41594
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
Applikations-hinweise WB 1:500 - 1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Glutamate Receptor, Metabotropic 5 (GRM5) antibody (ABIN6572027) Western blot analysis of extracts of various cell lines, using GRM5 antibody.
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