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SOCS1 Antikörper

SOCS1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6571338
  • Target Alle SOCS1 Antikörper anzeigen
    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
    Reaktivität
    • 53
    • 37
    • 31
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    Human, Maus, Ratte
    Wirt
    • 50
    • 5
    • 2
    Kaninchen
    Klonalität
    • 54
    • 3
    Polyklonal
    Konjugat
    • 37
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SOCS1 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 20
    • 16
    • 10
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant Protein of human SOCS1
    Isotyp
    IgG
    Top Product
    Discover our top product SOCS1 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
    Andere Bezeichnung
    SOCS1 (SOCS1 Produkte)
    Hintergrund

    Synonyms: CISH 1,CISH1,Cytokine inducible SH2 protein 1,JAB,JAK binding protein,JAK-binding protein,Janus kinase binding protein,SOCS 1,SOCS-1,Socs1,SOCS1,SSI 1,SSI-1,SSI1,STAT induced STAT inhibitor 1,STAT-induced STAT inhibitor 1,Suppressor of cytokine signaling 1,Supressor of cytokine signalling 1,TEC interacting protein 3,Tec-interacting protein 3,TIP 3,TIP-3,TIP3

    Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

    Molekulargewicht

    Observed_MW: 24kDa

    Calculated_MW: 23kDa

    Gen-ID
    8651
    UniProt
    O15524
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, TLR Signalweg, Response to Growth Hormone Stimulus
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