PLK1 Antikörper (Polo-Like Kinase 1)

Details for Product anti-PLK1 Antibody No. ABIN6569266
Target
Reaktivität
Human, Maus, Ratte
168
82
76
10
9
7
6
6
5
5
3
3
1
1
1
1
1
1
1
1
1
1
Wirt
Kaninchen
128
32
9
1
Klonalität
Polyklonal
Konjugat
Dieser PLK1 Antikörper ist unkonjugiert
10
7
6
6
5
5
5
5
5
4
3
3
2
2
2
2
2
Applikation
Immunofluorescence (IF), Western Blotting (WB)
119
66
50
27
25
23
22
12
3
3
3
2
2
1
1
Optionen
Immunogen Recombinant protein of human PLK1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PLK1
Hintergrund

Synonyms: Cell cycle regulated protein kinase,PLK 1,PLK,PLK-1,plk1,PLK1,Polo like kinase 1,Polo-like kinase 1,Serine/threonine protein kinase 13,Serine/threonine protein kinase PLK1,Serine/threonine-protein kinase 13,Serine/threonine-protein kinase PLK1,STPK 13,STPK13

Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy.

Molekulargewicht

Observed_MW: 65kDa

Calculated_MW: 68kDa

Gen-ID 5347
UniProt P53350
Pathways Zellzyklus, M Phase
Applikations-hinweise WB 1:500 - 1:2000 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Polo-Like Kinase 1 (PLK1) antibody (ABIN6569266) Western blot analysis of extracts of various cell lines, using PLK1 antibody.
Image no. 2 for anti-Polo-Like Kinase 1 (PLK1) antibody (ABIN6569266) Immunofluorescence analysis of U2OS cells using PLK1 antibody.